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Posted by on Jun 14, 2013 in Medical Journals |

Ivory vertebra and systemic mastocytosis.

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Joint Bone Spine. 2012 May;79(3):319-21. doi: 10.1016/j.jbspin.2012.01.003. Epub 2012 Feb 25.

Ivory vertebra and systemic mastocytosis.

Frenzel L, Suarez F, Chandesris MO, Hermine O.


The ivory vertebra sign seen on a standard radiograph of the spine should prompt investigations for a cause, which is most likely to be a bone metastasis, a lymphoma, or Paget's disease of bone. A diagnosis of idiopathic ivory vertebra can be given if no cause is identified. We report an unusual case of ivory vertebra sign that was due to systemic mastocytosis and improved with specific treatment. Although osteoporosis is the most common bone abnormality in systemic mastocytosis, an isolated sclerotic or lytic lesion may be found. The ivory vertebra sign should not be considered idiopathic until tests are done for mastocytosis, particularly given the availability of effective treatments.

Copyright © 2012 Société française de rhumatologie. Published by Elsevier SAS. All rights reserved.

PMID: 22366148 [PubMed – indexed for MEDLINE]